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Children’s of Alabama and University of Alabama at Birmingham Study Shows Association with a 30% Reduction in Mechanical Ventilation Using Etiometry’s Clinical Intelligence Platform

The study also observed a 20% decrease in overall hospital length of stay for post-surgical patients

A newly published study in the Journal of Pediatric Critical Care (JPCC) has demonstrated that integrating Etiometry’s Clinical Intelligence Platform at the Children’s Hospital of Alabama observed association with significantly improved patient outcomes in the pediatric cardiac intensive care unit (ICU). The study observed a 30% reduction in mechanical ventilation duration and a 20% decrease in overall hospital length of stay for post-surgical patients.

The research, titled Automated Spontaneous Breathing Trial Performance Tool is Associated with Improved Outcomes Following Pediatric Cardiac Surgery: A Single-Center Retrospective Study from Alabama, USA, evaluated the implementation of an automated spontaneous breathing trial (SBT) performance tool from Etiometry’s Clinical Intelligence Platform. This innovative approach leverages near real-time clinical and ventilator data to automate the hospital’s Extubation Readiness Test (ERT) practices, driving more timely initiation and more consistent adherence to the practices. This results in both reduced time on mechanical ventilation and length of hospital stay.

The study's findings indicate that the deployment of Etiometry’s SBT tool was associated with a significant reduction in postoperative total ventilation time (TOV) and length of stay (LOS). Specifically, the incidence rate for postoperative TOV was 0.7 times lower post-implementation (P < 0.0001), and the postoperative LOS was reduced by 20% (0.81 times, P < 0.01). The single-center study’s significant dataset of 787 pediatric patients makes the findings highly relevant for this patient population.

“The observed reduction in the duration of mechanical ventilation in this study may be clinically meaningful,” said Dr. Santiago Borasino, medical director of the cardiovascular intensive care unit at Children’s of Alabama professor at the University of Alabama at Birmingham, and the study’s principal investigator. “When we are able to reduce a patient’s time on mechanical ventilation, we are also decreasing their risk of complications such as pneumonia and potentially helping them recover faster and shorten their stay in the ICU. These improved patient outcomes benefits translate to freeing up ICU resources and ultimately, cost savings for hospitals.

The results of this study highlight the impact of integrating automated clinical intelligence tools into ICU workflows. By enabling proactive decision-making, Etiometry’s platform empowers care teams to optimize mechanical ventilation strategies, reducing hospital stays and improving patient outcomes.

To access the full study, visit:

https://journals.lww.com/jpcr/fulltext/2025/01000/automated_spontaneous_breathing_trial_performance.1.aspx.

About Children's of Alabama

Since 1911, Children’s of Alabama has provided specialized medical care for ill and injured children, offering inpatient, outpatient and primary care throughout Central Alabama. Ranked among the best children’s hospitals in the nation by U.S. News & World Report, Children’s serves patients from every county in Alabama and nearly every state. Children’s is a private, not-for-profit medical center that serves as the teaching hospital for the University of Alabama at Birmingham (UAB) pediatric medicine, surgery, psychiatry, research and residency programs. The medical staff consists of UAB faculty and Children’s full-time physicians, as well as private practicing community physicians.

About Etiometry

Founded in 2010, Etiometry is a leader in clinical decision-support software designed to help clinicians in intensive care units make data-driven, proactive decisions. By leveraging advanced analytics and AI-powered insights, the company empowers care teams to detect subtle changes in patient conditions, prevent complications, and improve recovery times.

Etiometry has received ten FDA clearances and is trusted by leading healthcare institutions worldwide, including top-ranked academic medical centers and pediatric hospitals. The company is committed to advancing patient safety, improving clinical efficiency, and lowering the cost of care through smarter data utilization.

Etiometry’s risk analytics support clinician review of physiologic trends and may aid in awareness of patient trajectory. The platform does not diagnose or treat.

To learn more, visit www.etiometry.com.

These improved patient outcomes benefits translate to freeing up ICU resources and ultimately, cost savings for hospitals.

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